Creutzfeldt-Jakob disease (CJD) is one of the transmissible spongiform encephalopathies that lead to rapidly progressive dementia. CJD has a low prevalence, and the average survival is only 1 year ...

Our study identifies a conserved medullary network, comprising the Lat-RM and CauM, underlying forelimb movement control across species, while also revealing cortical differences potentially driven by ...

Children with epilepsy who also have an intellectual disability or mental handicap (a term preferred over the older term, "mental retardation") or cerebral palsy present a wider range of problems than ...

Deep brain stimulation is an effective treatment option for dystonia. While the internal pallidum is the standard target, more recently, the subthalamic nucleus has been targeted. We analyze a ...

Neurometabolic disorders (NMD) are a heterogeneous group of neurological conditions, arising from genetic disorders that involve metabolic pathways. These predominantly affect the nervous system, ...

Large-animal models show greater advantages than rodents in recapitulating human genetic diseases, primarily because of their higher similarity to humans in terms of anatomy, physiology and genetics.

Extrapyramidal symptoms, also called drug induced movement disorders, describe the side effects caused by certain antipsychotic and other drugs. Extrapyramidal symptoms, also called drug-induced ...