Objective: To define the subgingival microbial profile associated with Stage II generalized periodontitis using next-generation sequencing and to determine the relative abundance of novel periodontal ...

Hypertrophic cardiomyopathy (HCM) has traditionally been regarded as a disease of the sarcomere; however, it is in the midst of a paradigm shift with growing recognition of contributions beyond the ...

Soft Matter Chemistry, Department of Chemistry, Faculty of Science, University of Helsinki, A. I. Virtasen aukio 1, 00014 Helsinki, Finland Drug Research Program, Division of Pharmaceutical ...

The serotonin transporter (SERT) is the target of antidepressants and psychostimulants. Despite its importance in the nervous, cardiovascular, and gastrointestinal systems, there is no direct ...

Skeletal muscle contraction is governed by ryanodine receptor 1 (RyR1) channels. Ryanodine receptors (RyRs) are the largest ion channels known, with multiple interconnected regulatory domains. Single ...

Department of Chemical and Biological Engineering, Princeton University, Princeton, New Jersey 08544, United States More by J. Clay Hamill, Jr. Department of Chemical and Biological Engineering, ...

Root hairs are a low-cost way to extend root surface area (RSA), water and nutrient acquisition. This study investigated to what extend variation exists for root hair formation in rice in dependence ...

Partial soil nitrogen cycling pathways with an emphasis on denitrification and DNRA showing the enzymes involved and genes commonly used as markers. This review aims to summarize current knowledge of ...

IRGM, a human immunity-related GTPase, confers autophagic defence against intracellular pathogens by an unknown mechanism. Here, we report an unexpected mode of IRGM action. IRGM demonstrated ...