Abstract: Amplitude modulation (AM) is a technique that relies on varying the amplitude of the RF carrier in accordance with the baseband signal. The signal is thus embedded in the carrier?s amplitude ...

本研究针对恶性肿瘤放化疗抵抗这一临床难题，揭示了DNA损伤修复关键蛋白Ku80通过K568位点巴豆酰化(Kcr)与SUMO化动态转换调控DNA-PK复合体组装的新机制。研究人员发现辐射诱导HDAC8介导Ku80 K568cr去巴豆酰化，进而促进CBX4催化的SUMO化修饰，从而激活DNA-PKcs S2056自磷酸 ...

aKey Laboratory of Laboratory Medical Diagnostics, Chinese Ministry of Education, Chongqing Medical University, Chongqing 400016, China bDepartment of Laboratory Medicine, Liuzhou Traditional Chinese ...

Proper nuclear organization is critical for cardiomyocyte function, because global structural remodeling of nuclear morphology and chromatin structure underpins the development and progression of ...

Institute of Applied Synthetic Chemistry, OC-163, TU Wien, Getreidemarkt 9, 1060 Vienna, Austria ...

Interdisciplinary Program of Biomedical Sciences, Graduate School, Chulalongkorn University, Bangkok 10330, Thailand Center of Excellence in Systems Biology, Faculty of Medicine, Chulalongkorn ...

Radiotherapy is widely used as an indispensable treatment option for cervical cancer patients. However, radioresistance always occurs and has become a big obstacle to treatment efficacy. The reason ...

Persistent Link: https://ieeexplore.ieee.org/servlet/opac?punumber=6287639 ...