The mitotic spindle of the budding yeast Saccharomyces cerevisiae will probably be the first such organelle to be understood in molecular detail. Here we describe the mitotic spindle cycle of budding ...

In the process of replicating themselves, cells have another choice: do they want to make an identical copy and be left with two cells? Or do they want to make four “half-copies”, in preparation for ...

The Howard Hughes Medical Institute has named Grant King, PhD, a Hanna H. Gray Fellow — investing up to $1.5 million for up to eight years to help King achieve his goal of running his own lab. He is ...

Anyone who has ever lost track of some bread, produce or leftovers, and later returned to observe that nature has run its course, has experience using the five senses (eyes, nose, [hopefully less ...

What Is a Vaginal Wet Mount? A vaginal wet mount, also called a wet prep or vaginal smear, is a test done to find the cause of vaginitis, an inflammation of the vagina. Your doctor will usually order ...

Exogenous double-strand breaks (DSBs) induce a DNA damage response during mitosis as well as meiosis. The DNA damage response is mediated by a cascade involving Mec1/Tel1 (ATR/ATM) and Rad53 (Chk2) ...

In 1971, Eileen Smith was a 21-year-old dropout from Elmhurst College, broke and breaking out of a bad relationship. She was also accidentally pregnant. She wanted an abortion, but her options were ...

They live in bread dough. They die in your oven. At the grocery store, where you buy them, they sit in little glass jars, dormant on the shelf, waiting to be rehydrated so they can do their life’s ...

Here is a story, for quarantined times, about extremely tiny organisms that do some of their best work by burping into uncooked dough. In the end, if things go well, there is good bread. If things go ...

The mechanisms by which the majority of proteins are imported into the peroxisomal lumen are well known and are based on the recognition of short stretches of amino acids located either at the ...

Production of healthy gametes in meiosis relies on the quality control and proper distribution of both nuclear and cytoplasmic contents. Meiotic differentiation naturally eliminates age-induced ...