Contributed by George M. Church, July 15, 2018 (sent for review September 22, 2017; reviewed by Chase Beisel and John M. Marshall) CRISPR-based gene drive systems—genetic elements which could be ...

From our mathematical model, phenotypic divergence between the two populations depends on an interaction between migration and plasticity (the product of and g1, Equations (6), (A3) and (A9)), while ...

Objectives The aim of this study was to conduct a rapid systematic review and meta-analysis of estimates of the incubation period of COVID-19. Design Rapid systematic review and meta-analysis of ...

Data centers are deemed essential infrastructures for the digital economy and a wide variety of operational activities such as cloud computing & Artificial Intelligence, big data analytics, e-commerce ...

Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, CA, USA ...

Mathematical Model of the CRISPR Gene Drives We start with a Hardy–Weinberg model (42) and incorporate an MCR with 100 % conversion rate to construct a model for a well-mixed system. This model is the ...

7 Cognitive Impairment Research Group, Centre for Interventions in Infection, Inflammation & Immunity (4i), Graduate Entry Medical School, University of Limerick, Limerick, Ireland Correspondence to ...

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Background The acute:chronic workload ratio (ACWR) is commonly used to manage training load in sports, particularly to reduce injury risk. However, despite its extensive application as a prevention ...