The blood–brain barrier is a physiological barrier that can prevent both small and complex drugs from reaching the brain to exert a pharmacological effect. For treatment of neurological diseases, drug ...

Regulation of Gene Expression by RNA Processing Steps in Cancers ...

The White Plains, New York-based Burke Neurological Institute ceased research operations, citing funding problems, The Transmitter reported. A global brain bank study illustrated how genetic variants ...

Multi-omics and integrative approaches are increasingly being used to study biological systems in health and to unearth hitherto unknown molecular players in many complex genetic diseases including: ...

Thoracic aortic dissection (TAD) is a life-threatening aortic disease without effective medical treatment. Increasing evidence has suggested a role for NE (neutrophil elastase) in vascular diseases.

Background Dipeptidyl peptidase-4 inhibitors (DPP-4is) have been reported to exhibit therapeutic effects in Parkinson’s disease (PD), increasing their potential for drug repurposing. One aspect of PD ...

The brain fills in what is missing and is sometimes quite creative about it. I'm a Blind Rehab Specialist and always asked my clients if they see things that aren't there. They won't tell anyone ...

Contributed by Howard Y. Chang; received November 19, 2024; accepted February 20, 2025; reviewed by Jellert Gaublomme and David A. Quigley The spatial organization of cells within tissues plays a ...

Nicholas R. Metrus, MD, is a board-certified neurologist and neuro-oncologist. He currently serves at the Glasser Brain Tumor Center in Summit, New Jersey. A splitting headache typically feels severe ...