Irish biotech start-up Aerska has raised $21 million (€18 million) in seed funding to help develop ribonucleic acid-based therapies for degenerative neurological diseases that could treat, delay and ...

1 Institute of Biomedical and Clinical Sciences, St James’s University Hospital, University of Leeds, Leeds, UK 4 Institute of Cancer and Pathology, St James’s University Hospital, University of Leeds ...

The reversible and noncovalent nature of the interactions governing the structure and binding properties of nucleic acids mean that the fields of supramolecular chemistry and nucleic acid chemistry ...

With potential applications in materials and especially in light-responsive biomedicine that targets cancer tissue selectively, much research has focused on developing covalent conjugation techniques ...

Acid–base reactions are ubiquitous in nature. Understanding their mechanisms is crucial in many fields, from biochemistry to industrial catalysis. Unfortunately, experiments give only limited ...

Ketones are in equilibrium with a form known as an enol. The name enol derives from the fact that enols are a combination of a carbonyl (C=O) containing group, such as an aldehyde or ketone and an ...

To maintain homeostasis, the human body employs many physiological adaptations. One of these is maintaining an acid-base balance. In the absence of pathological states, the pH of the human body ranges ...

Terpenoid cyclases catalyze the most complex reactions in biology, in that more than half of the substrate carbon atoms often undergo changes in bonding during the course of a multistep cyclization ...

There are many ways to improve retention and selectivity in reversed-phase HPLC separations. Choosing the correct mobile phase is maybe the most important step. There are many ways to improve ...