Every time a cell divides, it must copy its entire genome so that each daughter cell inherits a complete set of DNA. During that process, enzymes known as polymerases race along the DNA to copy its ...

The DNA packed inside every human cell contains instructions for life, written in billions of letters of genetic code. Every time a cell divides, the complete code, divided among 46 chromosomes, must ...

Genomic instability arises when the faithful duplication and transmission of DNA is compromised, leading to mutations, chromosomal rearrangements and copy number variations with broad implications for ...

Mayo Clinic researchers have identified a protein that acts like a traffic controller for DNA, preventing damage during cell division - a discovery that could lead to new cancer therapies, according ...

Researchers found how the INO80 protein moves nucleosomes to specific positions that are important for gene regulation and DNA replication INO80 uses a unique mechanism for moving nucleosomes that ...

When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process can cause alterations in genomic DNA, promoting cellular ageing, cancer, ...

Every time a cell divides, it must copy its DNA with extraordinary precision. But this process is constantly challenged by DNA damage. Among the most dangerous lesions are DNA interstrand crosslinks ...

DNA doesn’t just sit still inside our cells — it folds, loops, and rearranges in ways that shape how genes behave. Researchers have now mapped this hidden architecture in unprecedented detail, showing ...