Migrating newborn neurons suffer routine double-strand DNA breaks from physical stress during brain development.

Researchers discover that the GPR3 receptor acts as an immediate-early gene to jumpstart neuron and synapse development.

Rho family GTPases constitute a subfamily of small guanine nucleotide-binding proteins that serve as molecular switches in the regulation of the actin cytoskeleton, membrane trafficking and gene ...

Combining microscopy, scanning, and deep learning enables more precise imaging of functional dynamics in neural networks of human cortical organoids.

New study by Chiba University, Japan in collaboration with Karolinska Institutet, Sweden, uncovers novel enhancer-promoter interactions that regulate gene expression during neuronal differentiation ...

An early burst of GPR3 activity helps convert short-term cellular signals into long-term programs that support neuron growth, ...

Neuropsychiatric disorders are becoming increasingly prevalent. Given their complex and multifactorial pathogenesis, there is an urgent need for effective and targeted therapies that can improve ...

The brain is the most complex organ in the human body. Different parts of the brain perform a variety of functions, all of which are necessary for it to operate in one way or another. These functions ...

Cells have surface receptors that couple with proteins and other molecules to initiate or inhibit certain behaviors. Typically, the number of these receptors increases as the cell matures, but ...

Scientists have uncovered evidence supporting a mechanism in which transposable elements (TEs), once considered "non-functional" DNA, may have contributed to the evolution and expansion of gene ...

A team of researchers from the Institute for Neurosciences, a joint center of the Spanish National Research Council (CSIC) and the Miguel Hernández University (UMH) of Elche, in collaboration with ...