Structure-based drug design (SBDD) aims to design small-molecule ligands that bind with high affinity and specificity to pre-determined protein targets. Generative SBDD methods leverage structural ...

Generative drug design facilitates the creation of compounds effective against pathogenic target proteins. This opens up the potential to discover novel compounds within the vast chemical space and ...

Why engineers are turning to system-level models. How high-fidelity digital twins help expose system-level issues. Where MBSE is experiencing the fastest adoption. The roles of AI and data science in ...

Implementing 3D model–based project development and delivery represents a transformative shift in construction practices, particularly for highway projects. 3D modeling brings immense potential for ...

How model-based systems engineering (MBSE) has improved system design. Thermal design and MBE come together. When considering systems-level design, it’s important to understand the criticality of the ...

Data analysis is enabling teams to make better decisions, and systems engineering is no different. Digital solutions have emerged to help engineers gather and analyze data from modeling, simulation, ...

Heavy machinery is entering a new phase where hydraulics, electronics and embedded software are engineered as one integrated system. Using model-based systems engineering (MBSE) as a framework to ...

ClassNK has released the “Guidelines for 3D Model-Based Approval (3DMBA)”, which summarizes the fundamental principles and standard practices for 3DMBA (3D Model-Based Approval), a next-generation ...

What if the future of artificial intelligence didn’t hinge on size but on ingenuity? In a world dominated by massive transformer models boasting hundreds of billions of parameters, the HRM 27M AI ...

This chapter of the conduct of research report presents a task-by-task breakdown of the approach and results of the work performed throughout NCHRP Project 10-113. Inclusive of reporting and ...

Well, we already have a thriving thread on how AI is going to change how SW gets written. Figured it's worth exploring a discusison on how MBSE is going to change how Systems work is done. Honestly, I ...