Integrins are heterodimeric transmembrane receptors that mediate adhesion to the extracellular matrix and engage bidirectional signalling across the plasma membrane. Activation is controlled by ...

Integrins are heterodimeric transmembrane receptors that mediate adhesion between cells and the extracellular matrix, orchestrating bidirectional signalling that governs cancer cell behaviour. In the ...

Concept figure summarizing the proposed regulatory axis connecting extracellular matrix mechanics to integrin signaling and receptor trafficking in joint cells. In a new review, researchers from ...

Atherosclerosis, a disease characterized by the accumulation of lipids and inflammatory cells in the arterial wall, is a significant cause of cardiovascular events. A key process in atherosclerosis is ...