Integrins are heterodimeric transmembrane receptors that mediate bidirectional communication between the extracellular matrix and intracellular signalling networks. In epithelia, they coordinate ...

The development and proper functioning of the kidney is dependent on the interaction of kidney cells with the surrounding extracellular matrix (ECM). These interactions are mediated by heterodimeric ...

Protein evolution occurs slowly via small incremental mutations—usually. However, dramatic changes can happen: for instance, a fragment of one protein getting copied into the middle of another. While ...