The ovary is not solely a site of gamete maturation and steroid production but also a dynamic immunological organ in which innate immune mechanisms interact closely with granulosa cell function.

The innate immune system constitutes the body’s first line of defence against invading pathogens and cellular stress. Central to this response are pattern recognition receptors (PRRs), including ...

Cancer immunotherapy, which primes the body's immune system to fight off tumors, has historically focused on harnessing T cells' natural ability to recognize and attack cancer cells. While this ...

New findings suggest the vaccine may reduce the production of pro-inflammatory mediators to bacterial, fungal or viral infections by reprogramming innate immune cells to regulate inflammation Trinity ...

Secondary infections caused by bacteria or viruses during hospital care remain a long-standing global challenge, despite advances in modern medicine. In particular, mixed bacterial–viral infections in ...

Phospholipases PLA1, PLA2, PLC, and PLD hydrolyze phospholipids to produce corresponding lysophospholipids and fatty acids. Red arrows indicate the corresponding hydrolysis sites. B) Phospholipases ...

When a transplanted organ arrives, it’s like a controlled burn that risks becoming a wildfire. The body’s innate immune system senses damage signals, like heat shock proteins (HSP70), and sounds the ...

A landmark study due to start in the coming months aims to test a method for rejuvenating our immune system in older age. The ...

Judging by the claims on the bottles, it’s easy to assume a simple zinc tablet is a quick fix for everything from the common ...

Many diseases affect men and women differently. Asthma tends to strike men earlier in life, yet more women develop asthma as they get older. Parkinson's is more common in men, but Alzheimer's is more ...

Trinity College Dublin researchers have found that the BNT162b2 COVID-19 vaccine may offer protection beyond its intended primary target. In a study recently published in the Clinical Immunology ...

We often judge our immune systems based on how many colds we catch in a year, but experts say that’s an oversimplification of what is a highly complex network of cells, tissues and organs that works ...