Nature

Unifying multi-sample network inference from prior knowledge and omics data with CORNETO

Understanding biological systems requires methods that extract interpretable insights from omics data. Networks offer a natural abstraction by representing molecules as vertices and their interactions ...
Nature

Integrating single-cell multi-omics and prior biological knowledge for a functional ...

The alternative text for this image may have been generated using AI. scV(D)J-seq not only is useful to illuminate disease or treatment responses but also provides valuable insights into lymphocyte ...
pharmaphorum

FDA prior knowledge guide seeks to speed cell, gene therapy

In the latest part of its plan to cut barriers to cell and gene therapy (CGT) development, the FDA has published draft guidance to help developers draw on "existing science" to reduce the need for ...
RAPS

FDA aims to speed gene therapy development with prior scientific knowledge guidance

The US Food and Drug Administration (FDA) has proposed guidance on the types of scientifically valid prior knowledge sponsors should consider when developing certain gene therapies (GT). The agency ...