Double-stranded RNA (dsRNA) is a common pathogen-associated molecular pattern (PAMP) generated as a by-product during RNA virus replication 1. To counteract viral invasion, cells have developed a ...

The type I interferon response is inactive during early mammalian development and becomes functional only after gastrulation. As a result, the totipotent and pluripotent embryonic stages remain ...

A Purdue University team has discovered a new therapeutic target for triple-negative breast cancer. The research, led by Kyle Cottrell, an assistant professor of biochemistry, spotlights ...