A Purdue University team has discovered a new therapeutic target for triple-negative breast cancer. The research, led by Kyle Cottrell, an assistant professor of biochemistry, spotlights ...

RNA-based medicines are one of the most promising ways to fight human disease, as demonstrated by the recent successes of RNA vaccines and double-stranded RNA (dsRNA) therapies. But while health care ...

Multiple forms of double-stranded RNA (blue, magenta, orange structures) cross cell membranes with the help of a conserved protein located in novel sites (colored by depth) throughout the roundworm's ...

Researchers uncover key mechanisms in gene regulation that may lead to better design of RNA-based medicines. RNA-based medicines are one of the most promising ways to fight human disease, as ...

A Novel, Double-stranded Small Interfering RNA Therapeutic Designed to Silence Apolipoprotein C-III in Familial Chylomicronemia Syndrome April 2nd 2026 ...

Double-stranded RNA (dsRNA) is a critical immunostimulatory impurity in mRNA production and poses a problem for the downstream purification methods vital to manufacturing mRNA vaccines and ...

Their findings, published in Molecular Cell March 17, could open new pathways for treating autoimmune diseases and enhancing cancer immunotherapy. ADAR1 converts adenosine to inosine in ...

Building on its success against COVID-19, mRNA technology holds promise for novel vaccines and treatments targeting various diseases. However, a critical challenge remains: current in vitro ...

There are many molecules with therapeutic potential, but it can be a challenge to deliver them to the right places at the right times. RNA is one such molecule; the sequences for different proteins ...

Long before dinosaurs munched on leafy greens or photosynthesizing algae soaked up the sun, a lifeless soup of simple molecules floated through the watery and rocky landscape of early planet Earth.