内源性双链RNA（dsRNA）是具有免疫原性的自身分子，在病理条件下可驱动异常的免疫激活。然而，dsRNA在体内如何被调控以及对衰老的影响，目前尚不清楚。2026年5月25日，来自韩国科学技术院的研究团队在 Molecular Cell 杂志发表题为”Phenylalanyl-tRNA synthetase FARS-1/FARSA balances longevity and immunity ...

Double-strand breaks (DSBs) are toxic lesions that lead to genome instability. While canonical DSB repair pathways typically operate independently of RNA, growing evidence suggests that RNA:DNA ...

DNA DSBs are toxic lesions that are highly detrimental for the maintenance of genomic integrity, holding the potential to generate mutations, copy number alterations and translocations. DSBs are ...

A Purdue University team has discovered a new therapeutic target for triple-negative breast cancer. The research, led by Kyle Cottrell, an assistant professor of biochemistry, spotlights ...

What is the full form of RNA? Explore its meaning, single-stranded structure, functions, how it differs from DNA, its role in ...

Multiple forms of double-stranded RNA (blue, magenta, orange structures) cross cell membranes with the help of a conserved protein located in novel sites (colored by depth) throughout the roundworm's ...

Researchers uncover key mechanisms in gene regulation that may lead to better design of RNA-based medicines. RNA-based medicines are one of the most promising ways to fight human disease, as ...

A Novel, Double-stranded Small Interfering RNA Therapeutic Designed to Silence Apolipoprotein C-III in Familial Chylomicronemia Syndrome April 2nd 2026 ...

Double-stranded RNA (dsRNA) is a critical immunostimulatory impurity in mRNA production and poses a problem for the downstream purification methods vital to manufacturing mRNA vaccines and ...

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There are many molecules with therapeutic potential, but it can be a challenge to deliver them to the right places at the right times. RNA is one such molecule; the sequences for different proteins ...

Long before dinosaurs munched on leafy greens or photosynthesizing algae soaked up the sun, a lifeless soup of simple molecules floated through the watery and rocky landscape of early planet Earth.