Researchers have identified the specific structural loops in G-quadruplex DNA that allow it to act as a chaperone, preventing ...

MSK researchers are shedding new light on G-quadruplexes, a type of secondary DNA structure that can cause DNA replication to stall. The structures are a potential therapeutic target in cancer. Image ...

What scientists long believed were knots in DNA may actually be persistent twists formed during nanopore analysis, revealing an overlooked mechanism with major implications.

DNA isn't just a long string of genetic code, but an intricate 3D structure folded inside each cell. That means the tools used to study DNA need to be just as sophisticated-able to read not only the ...

New work from UC Davis and the University of Utah shows how the 3D structure of DNA inside a germ cell commits it to develop into a sperm cell. The discovery could improve understanding of fertility ...

For James Watson, DNA was everything — not just his life's work, but the secret of life itself. Over his long and storied career, Watson arguably did more than any other scientist to transform a ...

Estrogen is known as an important hormone, and it can control many cellular and bodily functions by regulating the activity of hundreds of genes. Scientists have now learned more about how estrogen ...

To our immune system, a potentially lifesaving gene therapy can look a lot like a dangerous infection. That's because most genetic medicine uses viruses or double-stranded DNA to deliver genetic ...