Bone fracture healing is a dynamic process that relies on coordinated cellular interactions for effective tissue regeneration. We employ optimized spatial transcriptomics to delineate the locations ...

Myocardial reperfusion is the primary treatment for myocardial ischemia. Multiple modes of cell death, such as apoptosis, necroptosis, autophagy, pyroptosis, and ferroptosis, occur following ...

T cell activation—the process by which these key immune defenders recognize threats and mobilize against them—depends on exquisitely timed molecular signals. Now researchers have captured one of the ...

Senescent "zombie" cells are essential architects required to build and maintain the brain's protective barriers.

Full-body defense does not always look the way textbooks say it should. In planarian flatworms, a newly identified cell type ...

Sepsis is a complex clinical syndrome characterized by dysregulated immune responses, systemic inflammation, and multi-organ dysfunction. It involves intricate interactions among multiple signaling ...

Scientists at the Max Planck Florida Institute for Neuroscience (MPFI), in collaboration with ZEISS and MetaCell, have developed a powerful new imaging pipeline called Neuroplex. As described in a ...

A new 3D human brain tissue platform developed by MIT researchers is the first to integrate all major brain cell types, including neurons, glial cells and the vasculature into a single culture. Grown ...