To understand how oncogenes affect genome organization, it is essential to visualize fundamental processes such as DNA replication and transcription at high resolution in intact cells. At the same ...

Many organisms have three biological rhythms with an approximately 24-h cycle: the transcription-translation feedback loop (TTFL) of clock genes (hereafter referred to as the circadian clock), the ...

A simulated cell in the early stages of division. Left half shows cytoplasm (blue cubes), mRNA degradation machinery molecules (pink), and sugar transporters (brown). Right half adds the membrane ...

Five years ago, scientists watched in wonder as synthetic bacteria grew and split into daughter cells. The bacteria’s extremely stripped-down genome still supported its entire life cycle. It was a ...