The Wnt signalling pathway governs key processes in embryonic development, tissue homeostasis and stem cell maintenance by regulating gene expression through β-catenin–dependent and ...

Gene expression is finely controlled by the abundance and activation status of transcription factors and their regulators, as well as by a number of reversible modifications of DNA and histones that ...

A research team led by Prof. Liu Qingsong at the Institute of Health and Medical Technology, the Hefei Institutes of Physical ...

Image Caption: Controversial effects of the STING pathway in colitis development. In colon cancer, the pathway shows a similarly complex profile. Activation of STING can stimulate immune defenses that ...

Researchers at WashU Medicine identified a direct connection between cancer-related inflammation and the loss of motivation characteristic of advanced cancer. In a mouse study, they describe a brain ...

Researchers identified a direct connection between cancer-related inflammation and the loss of motivation characteristic of advanced cancer. In a mouse study, they describe a brain pathway that starts ...

Signal transduction The cellular process that converts a signal, such as a hormone, growth factor, neurotransmitter, cytokine, mechanical force, or environmental cue, into biochemical changes inside ...