New research has identified the specific biological mechanism behind the muscle dysfunction found in myotonic dystrophy type 1 (DM1) and further shows that calcium channel blockers can reverse these ...

The type 1 ryanodine receptor (RyR1) is an important calcium release channel in skeletal muscles essential for muscle contraction. It mediates calcium release from the sarcoplasmic reticulum, a ...

New research has identified the specific biological mechanism behind the muscle dysfunction found in myotonic dystrophy type 1 (DM1) and further shows that calcium channel blockers can reverse these ...

If you are thinking about stopping taking blood pressure medication, there are some important facts to know. Two experts ...

Ion channels are structures within cell membranes that enable specific ions to travel to and from the cell. Such transfer is essential for a variety of physiological processes such as muscle cell ...

When three bright minds from different disciplines come together, something exceptional can happen. This is exactly what Prof. Patricia Hidalgo, Dr. Beatrix Santiago-Schübel, and Dr. Mercedes ...

A compound -- one of 27 million screened in a library of potential new drugs -- reversed four types of chronic pain in animal studies, according to new research. The small molecule, which binds to an ...

A woman with hopes to conceive was diagnosed with severe vasospastic angina (VSA); however, she was able to carry a healthy baby to full term without angina attacks after starting treatment of a ...

Background Hypertension is highly prevalent among patients with chronic kidney disease (CKD) and contributes substantially to ...

Calcium channel blockers constitute a class of antihypertensive agents that inhibit voltage-dependent calcium influx in vascular smooth muscle and renal cells. In patients with hypertensive kidney ...