The first "blueprint" of human skeletal development reveals how the skeleton forms, shedding light on the process of arthritis, and highlighting cells involved in conditions that affect skull and bone ...

Bones are the living tissue on which the human skeleton is constructed and play a key role in enabling physical movements. The structural integrity of bones has been attributed to bone remodeling-aa ...

Full view of how bones and joints form in the first trimester uncovers cells and pathways that could help diagnose and treat skeletal conditions in the future. The first 'blueprint' of human skeletal ...

An illustration of bone and bone marrow development. During the process, osteoclasts (cells in blue) expand the marrow cavity by absorbing and removing unnecessary bone. In this study, the team found ...

Skeletal conditions such as developmental dysplasia of the hip (DDH), osteoporosis, and osteoarthritis affect millions worldwide, often causing chronic pain and disability. These disorders stem from ...

In the elderly, a multitude of factors contribute to diminished bone regeneration capabilities, including a reduction in the self-renewal and differentiation abilities of mesenchymal stem cells, an ...

A pair of proteins could contribute to the development of healthy, strong bones by directing early cell movement and blood vessel generation. A pair of proteins, YAP and TAZ, has been identified as ...

Blood cancers such as leukemia are caused by genetic changes in the blood-forming stem cells of the bone marrow. Scientists at the University Medical Center Mainz have now shown how chronic ...