Alzheimer’s disease (AD) is an age-related neurodegenerative disorder with regulatory RNAs playing significant roles in its etiology. Circular RNAs (CircRNA) are enriched in human brains and ...
In eukaryotic cells, circular RNAs (circRNAs) are produced primarily by back-splicing events of pre-mRNAs 1. Nascent pre-mRNAs are produced by RNA polymerase II and undergo multiple processing steps ...